Some Concussion and Hyperbaric Oxygen Research:

“Hyperbaric Oxygen Therapy (HBOT) for Reduction of Secondary Brain Damage in Head Injury” 

—Journal of Neurotrauma, 21:44-48. 2004  

Conclusion: Translational research of HBOT in a variety of Traumatic Brain Injuries (TBI) models has shown neuroprotective effects 

in the absence of increased oxygen toxicity. Recent clinical trials favour HBOT as promising safe therapeutic strategy for severe TBI patient.  

“Hyperbaric Oxygen Therapy can improve Post Concussion Syndrome years after Mild Traumatic Brain Injury – Randomised Prospective Trial” www.ncbi.nlm.nih.gov/pubmed/24260334 

—PLoS One November 2013 10.137/journal.pone 0079995 

Conclusion: Convincing results based on a crossover study, demonstrating that HBOT can induce neuroplasticity and significant brain function improvement in mild TBI patients with prolonged Post-Concussion-Syndrome at late chronic stage, years after injury. 

The findings here bear the promises that HBOT can be effective in treating other brain impairments like PTSD or repairing radiation damage. It is reasonable to expect that HBOT can help slow down or even reverse metabolic disorders associated with neurodegenerative diseases.